Pediatric Neuro-Metabolic Test | Kite Health


The first-of-its-kind Pediatric Neuro-Metabolic Test uncovers gut–brain–immune imbalances in autism and ADHD by measuring microbial and immune metabolites in urine—with a stool add-on for deeper insights.

The Neuro-Metabolic Test

A first-of-its-kind Pediatric Neuro-Metabolic Test exploring the Gut–Brain–Immune connection

Before diving into the science, picture your child’s body as a house with three connected rooms—gut, brain, and immune system. Whatever happens in one room echoes in the others: tummy distress can stir up mood swings, brain stress can inflame the gut, and immune “alarms” can make both rooms extra sensitive.

This three-way conversation is called the gut–brain–immune axis, and our Neuro-Metabolic Test makes it visible for the first time in a child-friendly way—through a simple urine strip.

Why Gut–Brain–Immune Matters in Autism and ADHD

Research shows that many autistic children and those with ADHD present with:
Microbial shifts

fewer supportive species and more irritant-producers.

Immune footprints in urine

para-cresol, kynurenine detours, oxidative stress markers tied to sleep and behavior.

Bile acid imbalances

more primary bile acids, fewer microbial byproducts, suggesting inflammation and reduced diversity.

These patterns don’t “cause” autism or ADHD, but they can amplify challenges like tummy pain, sensory overload, or poor sleep.

Why Urine?

Blood tests measure immune cells directly, but urine shows the aftermath—tiny chemical traces of microbial activity, inflammation, and nutrient use. It’s painless, child-friendly, and powerful.

With the Neuro-Metabolic Test, Kite Health measures 100+ immune and microbial metabolites grouped into clear “clues”:
Signal in Urine
Neopterin (immune activation marker)
Neopterin (immune activation marker)
Neopterin (immune activation marker)
Neopterin (immune activation marker)
Neopterin (immune activation marker)
Neopterin (immune activation marker)
Signal in Urine
Immune system is “on alert,” possible chronic inflammation
Stress pathway diverting tryptophan away from serotonin
High immune-driven oxidative damage
Neopterin (immune activation marker)
Neopterin (immune activation marker)
Neopterin (immune activation marker)
Signal in Urine
Neopterin (immune activation marker)
Neopterin (immune activation marker)
Neopterin (immune activation marker)
Neopterin (immune activation marker)
Neopterin (immune activation marker)
Neopterin (immune activation marker)

Why families like yours are essential

Kids on the autism spectrum have unique biology that standard adult lab tests miss. Without data from the right families:
1
Targeted food plans (fiber for missing microbes, oxalate-lowering diets, etc).
2
Strain-specific probiotic.  Unlimited cards
3
Nutrient support (B6, B12, antioxidants, etc).
4
Lifestyle tweaks to calm the gut–brain–immune loop.

Stool Add-On: Where to act in the Neighborhood?

For families or practitioners who want a deeper look at the gut’s residents, Kite offers a stool metabolomics add-on.
For families or practitioners who want a deeper look at the gut’s residents, Kite offers a stool metabolomics add-on.

While urine shows what’s happening chemically, stool reveals where to act in the gut. The stool kit checks for:
SCFA production and balance – “fuel” for the gut lining and immune system.
Nontoxicity – whether microbes are producing irritants.
Stability – whether microbes are producing irritants.
Unlimited cards

Why combine both?

Urine = what’s happening.
Stool = where to act.

Together, they connect cause and effect—
turning puzzle pieces into a clear action plan.

Why it’s next generation:

Deeper coverage
More biomarkers than other panels.
Faster turnaround
2× quicker than legacy workflows.
Neurodevelopment focus
Results linked to behaviors families actually see.
Child-friendly
Simple urine strip; optional stool for more insight.
The result: Unprecedented clarity—no guesswork, no extra kits, just actionable insight where gut, immune response, metabolism, and brain meet.